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Guggulsterone induces apoptosis in colon cancer cells and inhibits tumor growth in murine colorectal cancer xenografts

โœ Scribed by Min Ji An; Jae Hee Cheon; Seung Won Kim; Eun Soo Kim; Tae Il Kim; Won Ho Kim

Book ID
116335131
Publisher
Elsevier Science
Year
2009
Tongue
English
Weight
637 KB
Volume
279
Category
Article
ISSN
0304-3835

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## Abstract Statins, HMGโ€CoA reductase inhibitors could be associated with the risk reduction of colorectal cancer. We previously demonstrated that simvastatin inhibits NFโ€ฮบB signaling in human intestinal epithelial cells and ameliorates acute murine colitis. The aim of our study was to evaluate th