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Guanosine-5′-monophosphate induces cell death in rat hippocampal slices via ionotropic glutamate receptors activation and glutamate uptake inhibition

✍ Scribed by Simone Molz; Tharine Dal-Cim; Carla I. Tasca

Book ID
116765347
Publisher
Elsevier Science
Year
2009
Tongue
English
Weight
252 KB
Volume
55
Category
Article
ISSN
0197-0186

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## Abstract Excitotoxicity and cell death induced by glutamate are involved in many neurodegenerative disorders. We have previously demonstrated that excitotoxicity induced by millimolar concentrations of glutamate in hippocampal slices involves apoptotic features and glutamate‐induced glutamate re