Mammalian ribonucleotide reductase catalyzes the rate-limiting for the de novo synthesis 2'-deoxyribonucleoside 5'-triphosphates. There is some suggestion that this step may also be the rate-limiting step of DNA synthesis. It is apparent that the level of the enzyme, ribonucleotide reductase, varies
Guanine ribonucleotide depletion in mammalian cells
✍ Scribed by Binh T. Nguyen; Marvin B. Cohen; Wolfgang Sadée
- Publisher
- Springer
- Year
- 1983
- Tongue
- English
- Weight
- 227 KB
- Volume
- 11
- Category
- Article
- ISSN
- 0344-5704
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