𝔖 Bobbio Scriptorium
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GTP-cyclohydrolase and cytokine gene expression in NEC

✍ Scribed by A. Stanford; E.P. Nadler; X.R. Zhang; H.R. Ford


Book ID
114123650
Publisher
Elsevier Science
Year
2000
Tongue
English
Weight
143 KB
Volume
57
Category
Article
ISSN
0149-7944

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Tetrahydrobiopterin deficiencies are highly heterogeneous disorders, with more than 30 molecular lesions identified in the past 2 years in the GTP cyclohydrolase I and 6-pyruvoyl-tetrahydropterin synthase genes. The spectrum of mutations causing a reduction of these two biosynthetic enzymes is revie