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GTP binding and hydrolysis by the signal recognition particle during initiation of protein translocation

✍ Scribed by Miller, Joshua D.; Wilhelm, Heike; Gierasch, Lila; Gilmore, Reid; Walter, Peter

Book ID
109786954
Publisher
Nature Publishing Group
Year
1993
Tongue
English
Weight
487 KB
Volume
366
Category
Article
ISSN
0028-0836

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The functions of G proteins--like those of bacterial elongation factor (EF) Tu and the 21 kDa ras proteins (p21ras)--depend upon their abilities to bind and hydrolyze GTP and to assume different conformations in GTP- and GDP-bound states. Similarities in function and amino acid sequence indicate tha