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GSTT2promoter polymorphisms and colorectal cancer risk

✍ Scribed by Sang-Geun Jang; Il-Jin Kim; Hio Chung Kang; Hye-Won Park; Sun-A Ahn; Hyun-Ju Yoon; Kun Kim; Hai-Rim Shin; Jin Soo Lee; Jae-Gahb Park

Book ID
115011034
Publisher
BioMed Central
Year
2007
Tongue
English
Weight
287 KB
Volume
7
Category
Article
ISSN
1471-2407

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## Abstract Isothiocyanates (ITCs) are nonnutrient compounds in cruciferous vegetables with anticarcinogenic properties. ITCs down‐regulate cytochrome P‐450 biotransformation enzyme levels, activate Phase II detoxifying enzymes and induce apoptosis. On the other hand, ITCs also serve as a substrate