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GSH depletion enhances adenoviral bax-induced apoptosis in lung cancer cells

โœ Scribed by Honda, Tsuyoshi; Coppola, Simona; Ghibelli, Lina; Cho, Song H; Kagawa, Shunsuke; Spurgers, Kevin B; Brisbay, Shawn M; Roth, Jack A; Meyn, Raymond E; Fang, Bingliang

Book ID
110019089
Publisher
Nature Publishing Group
Year
2004
Tongue
English
Weight
213 KB
Volume
11
Category
Article
ISSN
0929-1903

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## Abstract The fragile histidine triad (__FHIT__) gene is a frequent target of deletions in lung cancer. Previous studies have shown that __FHIT__ gene transfer into lung cancer cells lacking FHIT expression results in induction of apoptosis. However, the effect of FHIT expression on apoptosis ind