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Growth suppression and induction of heat-shock protein-70 by 9-cis β-carotene in cervical dysplasia-derived cells

✍ Scribed by Toshinari Toba; Yoshihiro Shidoji; Jun Fujii; Hisataka Moriwaki; Yasutoshi Muto; Takehiko Suzuki; Nobuko Ohishi; Kunio Yagi

Book ID
117175159
Publisher
Elsevier Science
Year
1997
Tongue
English
Weight
634 KB
Volume
61
Category
Article
ISSN
0024-3205

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Exposure of 9L rat brain tumor cells to 40-100 µM CdCl 2 for 2 h leads to an induction of a wide spectrum of heat shock proteins (HSPs). We have demonstrated that induction of the 70-kDa HSP (HSP70) and enhanced expression of its cognate (HSC70) by cadmium are concentration dependent and that the in