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Growth signals in liver regeneration

✍ Scribed by BAO-HONG ZHANG

Book ID
108949371
Publisher
John Wiley and Sons
Year
1997
Tongue
English
Weight
307 KB
Volume
12
Category
Article
ISSN
0815-9319

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Transforming growth factor ␀ (TGF-␀) is a potent inhibitor of hepatocyte proliferation in vitro and is suggested to be a key negative regulator of liver growth. To directly address the role of TGF-␀ signaling in liver regeneration in vivo, the TGF-␀ type II receptor gene (Tgfbr2) was selectively del