Growth-inhibitory glycopeptides obtained from the cell surface of cultured chick embryo fibroblasts
β Scribed by Yoshihito Yaoi
- Book ID
- 115891870
- Publisher
- Elsevier Science
- Year
- 1984
- Tongue
- English
- Weight
- 554 KB
- Volume
- 154
- Category
- Article
- ISSN
- 0014-4827
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There is no cell proliferation in very sparcely plated chick embryo cell cultures. Substituting conditioned medium or adding of ethanol-fixed homologous cells to the cultures accelerates cell colony growth. The mechanism for the mitogenic action of fixed cells is considered to be the contact stimula
## Abstract Initiation of proliferation in densityβinhibited chick embryo fibroblast cultures induced by insulin or trypsin was partially reversed by replacing the medium with supernatants from parallel nonβstimulated cultures. Growth stimulation by neuraminidase, pokeweed mitogen, bacterial lipo p