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Growth inhibition of estrogen receptor-positive and aromatase-positive human breast cancer cells in monolayer and spheroid cultures by letrozole, anastrozole, and tamoxifen

โœ Scribed by Ikuko Kijima; Toru Itoh; Shiuan Chen


Book ID
116697723
Publisher
Elsevier Science
Year
2005
Tongue
English
Weight
673 KB
Volume
97
Category
Article
ISSN
0960-0760

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## Abstract Although tamoxifen (TAM) is used for the frontโ€line treatment and prevention of estrogen receptorโ€positive (ER+) breast tumors, nearly 40% of estrogenโ€dependent breast tumors do not respond to TAM treatment. Moreover, the positive response is usually of short duration, and most tumors e