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Growth inhibition by methionine analog inhibitors of S-adenosylmethionine biosynthesis in the absence of polyamine depletion

✍ Scribed by Carl W. Porter; Janice R. Sufrin; Dennis D. Keith


Book ID
115757465
Publisher
Elsevier Science
Year
1984
Tongue
English
Weight
466 KB
Volume
122
Category
Article
ISSN
0006-291X

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Methionine metabolism in BHK cells: Prel
✍ Dr. Michel Caboche; Jacques Hatzfeld πŸ“‚ Article πŸ“… 1978 πŸ› John Wiley and Sons 🌐 English βš– 732 KB

## Abstract Cycloleucine is in vitro a competitive inhibitor of methionine adenosyltransferase, an enzyme involved in S‐adenosylmethionine biosynthesis. The physiological effects of this drug on baby hamster kidney cells have been studied. When cells are grown in a medium containing 10 ΞΌM methionin