## Background: Mice transgenic for growth hormone develop mesangial proliferation, glomerular hypertrophy, and progressive glomerular sclerosis suggesting that the growth hormone-insulin-like growth factor i (igf-i) pathway plays an important role. therefore, we studied the impact of variable conce
β¦ LIBER β¦
Growth hormone receptor polymorphism and the effects of pegvisomant in acromegaly
β Scribed by Antonio Bianchi; Gherardo Mazziotti; Laura Tilaro; Vincenzo Cimino; Flora Veltri; Eleonora Gaetani; Giovanni Pecorini; Alfredo Pontecorvi; Andrea Giustina; Laura De Marinis
- Publisher
- Springer US
- Year
- 2008
- Tongue
- English
- Weight
- 187 KB
- Volume
- 12
- Category
- Article
- ISSN
- 1386-341X
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Growth hormone receptor (GHR) has a major role in the regulation of growth hormone action, and thus, is an obvious candidate gene associated with milk production traits in mammals. The present authors have sequenced 273 bp of the 3β² flanking region of the bovine __GHR__, and found three length varia