Insulin-Like growth factor I and protein
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Edward C. Dempsey; Kurt R. Stenmark; Ivan F. McMurtry; Richard F. O'Brien; Norbe
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Article
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1990
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John Wiley and Sons
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English
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Smooth muscle cell (SMC) hyperplasia is an important component of vascular remodeling in chronic hypoxic pulmonary hypertension. The mechanisms underlying SMC proliferation in the remodeling process are poorly understood, but may involve insulin-like growth factor I (ICF-I). This study investigates