Despite roughly thirty years of experience with growth management programs, which are basically land-use planning tools, most U.S. communities do not plan for how best to limit or manage rapid growth; in fact, most communities do not plan at all. In the absence of planning, land-use boards, regulato
Growth Disorders, Second Edition
β Scribed by C. Kelnar, M. Savage, P. Saenger, C. Cowell
- Year
- 2007
- Tongue
- English
- Leaves
- 728
- Edition
- 2
- Category
- Library
No coin nor oath required. For personal study only.
β¦ Synopsis
Linear growth is a biological process of fundamental importance to the physical and psychological make-up of a child and adolescent but which can be subject to a number of interruptions and disorders. The management and treatement of patients with growth disorders constitutes a major, and important, part of practice in clinical pediatrics, while in public health terms growth assessment remains one of the most useful indices of health and economic well being in both developed and the developing world. This book approaches growth and its disorders from both a physiological and pathophsyiological standpoint. The book outlines in detail the fundamental biological mechanisms of normal and abnormal linear growth, how to assess growth accurately fundamental to the early detection of abnormatlity and, importantly, how to manage disorders leading to short and tall stature, and disorders of the timing of puberty. Throughout, emphasis is given on achieving a satisfactory outcome for the child and parent by keeping them fully informed as to what is possible from a particular treatment strategy. The result is a wide-ranging and balanced account of this challenging field drawing on the expertise of a team of international specialists from a variety of backgrounds.
β¦ Table of Contents
Book title......Page 2
Contents......Page 4
Contributors......Page 8
Foreword......Page 14
Preface to the first edition......Page 16
Preface to the second edition......Page 18
List of abbreviations used......Page 20
Colour plates between 280 and 281......Page 304
1 Historical background and worldwide perspectives......Page 24
PART 1: PHYSIOLOGY OF LINEAR GROWTH......Page 36
2 Cellular growth......Page 38
3 Bone and cartilage growth and metabolism......Page 48
4 Genetic control of growth......Page 71
5 Nutrition and growth......Page 95
6 Endocrinology of growth: Central control......Page 113
7 Peripheral hormone action......Page 137
8 Normal fetal growth......Page 150
9 Growth in infancy and childhood......Page 155
10 Growth at adolescence......Page 173
11 Growth references......Page 188
PART 2: GROWTH ASSESSMENT......Page 206
12 Abnormal growth: Definition, pathogenesis, and practical assessment......Page 208
13 Practical auxology and skeletal maturation......Page 231
14 Endocrine assessment and principles of endocrine testing......Page 242
15 Radiologic and imaging assessment of the skeletal dysplasias......Page 253
16 Psychological assessment......Page 264
PART 3: CHRONIC PEDIATRIC DISORDERS AND MANAGEMENT OF THE ASSOCIATED GROWTH DISTURBANCE......Page 280
17 Short stature syndromes......Page 282
18 Genetic and dysmorphic syndromes with increased stature......Page 312
19 Skeletal dysplasias......Page 322
20 Respiratory disorders......Page 348
21 Gastrointestinal disorders......Page 359
22 Renal disorders......Page 371
23 Metabolic bone diseases: Disorders of calcium and phosphate metabolism......Page 390
24 Diabetes......Page 403
25 Hemoglobinopathies......Page 417
26 Psychological disorders associated with short stature......Page 427
27 Etiology and management of growth failure in tropical and developing countries......Page 436
PART 4: ENDOCRINE CAUSES OF ABNORMAL GROWTH......Page 444
28 Abnormalities of growth hormone secretion......Page 446
29 Abnormalities of growth hormone action......Page 475
30 Growth and thyroid disorders......Page 490
31 Adrenal disorders......Page 498
32 Gonadal disorders......Page 503
PART 5: TREATMENT OF GROWTH DISORDERS......Page 512
33 Treatment of growth disorders: Growth hormone deficiency......Page 514
34 Idiopathic short stature......Page 527
35 Turner and Noonan syndromes: Disease-specific growth and growth-promoting therapies......Page 543
36 PraderβWilli syndrome: Disease-specific auxology and therapy......Page 557
37 Obesity in children and adolescents......Page 569
38 Diseases of growth in the child treated for cancer......Page 594
39 Growth hormone therapy in the short, small-for-gestational age child......Page 607
40 The evaluation and treatment of the child with precocious puberty......Page 616
41 Delay of growth and puberty......Page 626
42 Growth hormone insensitivity syndromes......Page 640
43 Growth hormone releasing peptides/secretogogues......Page 645
44 Aromatase inhibitors......Page 657
45 Metabolic side effects and adverse effects of growth hormone therapy......Page 669
46 Medical management of tall stature......Page 686
47 Surgical management of tall stature......Page 698
Appendix to Chapter 12......Page 705
A......Page 706
B......Page 707
C......Page 708
D......Page 710
E......Page 711
G......Page 712
H......Page 716
I......Page 717
L......Page 718
M......Page 719
N......Page 720
P......Page 721
R......Page 723
S......Page 724
T......Page 726
V......Page 727
Z......Page 728
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