Growth-dependent and PKC-mediated translational regulation of the upstream stimulating factor-2 (USF2) mRNA in hematopoietic cells

PI3K/Akt-dependent regulation of the tra

PI3K/Akt-dependent regulation of the transcription factor myocyte enhancer factor-2 in insulin-like growth factor-1- and membrane depolarization-mediated survival of cerebellar granule neurons

✍ M. Wiedmann; X. Wang; X. Tang; M. Han; M. Li; Z. Mao 📂 Article 📅 2005 🏛 John Wiley and Sons 🌐 English ⚖ 270 KB

## Abstract Survival signals such as insulin‐like growth factor‐1 (IGF‐1) or membrane depolarization convey their neuronal protective effects through the activation of signaling networks and nuclear factors. In cerebellar granule neurons, IGF‐1 mediates survival primarily through the PI3K/Akt pathw