✦ LIBER ✦

Growth and genetic stability of 4 temperature sensitive(ts)mutants of respiratory syncytial (RS) virus in newborn ferrets

✍ Scribed by R. B. Belshe; Linda S. Richardson; D. A. Prevar; Ena Camargo; R. M. Chanock

Publisher: Springer Vienna
Year: 1978
Tongue: English
Weight: 666 KB
Volume: 58
Category: Article
ISSN: 1432-8798
DOI: 10.1007/bf01317823

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Isolation and characterization of furthe

Isolation and characterization of further defective clones of a temperature sensitive mutant (ts-1) of respiratory syncytial virus

✍ Linda S. Richardson; T. J. Schnitzer; R. B. Belshe; Ena Camargo; D. A. Prevar; R 📂 Article 📅 1977 🏛 Springer Vienna 🌐 English ⚖ 569 KB

Evaluation of five temperature-sensitive

Evaluation of five temperature-sensitive mutants of respiratory syncytial virus in primates: II. Genetic analysis of virus recovered during infection

✍ Robert B. Belshe; Dr. Linda S. Richardson; William T. London; D. Lewis Sly; Ena 📂 Article 📅 1978 🏛 John Wiley and Sons 🌐 English ⚖ 516 KB

Five temperature-sensitive (ts) mutants of respiratory syncytial (RS) virus (ts-1, ts-1 NG-1, ts-1 NG-16, ts-2, and ts-7), previously evaluated forinfectivity and virulence in chimpanzees and owl monkeys, were also assayed for in vivo genetic stability. None of the five mutants tested was completely

Evaluation of five temperature-sensitive

Evaluation of five temperature-sensitive mutants of respiratory syncytial virus in primates: I. Viral shedding, immunologic response, and associated illness

✍ Dr. Linda S. Richardson; Robert B. Belshe; William T. London; D. Lewis Sly; Davi 📂 Article 📅 1978 🏛 John Wiley and Sons 🌐 English ⚖ 564 KB

## Abstract Approximately 10^4^ plaque‐forming units (pfu) of five temperature‐sensitive (__ts__) mutants of respiratory syncytial (RS) virus were administered intranasally to seronegative chimpanzees to evaluate their level of attenuation. When the __ts__‐1 mutant was given to two chimpanzees, the