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Growth and Gene Expression Are Predominantly Controlled by Distinct Regions of the Human IL-4 Receptor

✍ Scribed by John J Ryan; Lisa J McReynolds; Achsah Keegan; Lu-Hai Wang; Evan Garfein; Paul Rothman; Keats Nelms; William E Paul


Book ID
117723006
Publisher
Elsevier Science
Year
1996
Tongue
English
Weight
308 KB
Volume
4
Category
Article
ISSN
1074-7613

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The proximal promoter region of the human pituitary expressed growth hormone (GH1) gene is highly polymorphic, containing at least 15 single nucleotide polymorphisms (SNPs). This variation is manifest in 40 different haplotypes, the high diversity being explicable in terms of gene conversion, recurr