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Group I-intron trans-splicing and mRNA editing in the mitochondria of placozoan animals

✍ Scribed by Gertraud Burger; Yifei Yan; Pasha Javadi; B. Franz Lang

Book ID
113933044
Publisher
Elsevier Science
Year
2009
Tongue
English
Weight
673 KB
Volume
25
Category
Article
ISSN
0168-9525

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## Abstract ## Background Group I intron‐based __trans__‐splicing ribozyme, which can specifically reprogram human telomerase reverse transcriptase (hTERT) RNA, could be a useful tool for tumor‐targeted gene therapy. In the present study, the therapeutic feasibility of this ribozyme was investigat