Group additive contributions to the alcohol-induced α-helix formation of melittin: implication for the mechanism of the alcohol effects on proteins

The structure of the ends of α-helices i

The structure of the ends of α-helices in globular proteins: Effect of additional hydrogen bonds and implications for helix formation

✍ David P. Leader; E. James Milner-White 📂 Article 📅 2011 🏛 John Wiley and Sons 🌐 English ⚖ 451 KB

## Abstract We prepared a set of about 2000 α‐helices from a relational database of high‐resolution three‐dimensional structures of globular proteins, and identified additional main chain __i__ ← __i__+3 hydrogen bonds at the ends of the helices (i.e., where the hydrogen bonding potential is not fu