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Grip and Percussion Myotonia in Myotonic Dystrophy Type 1

โœ Scribed by Hughes, Brian N.; Hogue, Jacob S.; Hsieh, David T.


Book ID
122145789
Publisher
Elsevier Science
Year
2014
Tongue
English
Weight
263 KB
Volume
164
Category
Article
ISSN
1097-6833

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## Abstract Myotonic dystrophy (DM1), the most common adult muscular dystrophy, is a multisystem, autosomal dominant genetic disorder caused by an expanded CTG repeat that leads to nuclear retention of a mutant RNA and subsequent RNA toxicity. Significant insights into the molecular mechanisms of R