Grey matter atrophy in early versus late dementia in Parkinson's disease
β Scribed by M.K. Beyer; D. Aarsland
- Book ID
- 116820475
- Publisher
- Elsevier Science
- Year
- 2008
- Tongue
- English
- Weight
- 252 KB
- Volume
- 14
- Category
- Article
- ISSN
- 1353-8020
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## Abstract The purpose of this research was to examine the extent of global brain atrophy and white matter hyperintensities (WMH) in early Parkinson's disease (PD) compared to normal controls (NC), to explore the relationship between the MRI variables and cognition in PD. In this multicenter study
## Abstract We evaluated whether patients with earlyβonset Parkinson's disease (EOPD) have a different clinical profile and pharmacological response than those with lateβonset disease (LOPD). We performed a retrospective analysis and an acute pharmacological challenge with LβDopa in 34 EOPD (age at