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Gravity-flow alkaline elution: A method to rapidly detect carcinogen-induced DNA strand breaks

✍ Scribed by Jeffrey R. Hincks; Roger A. Coulombe Jr.

Book ID
115759384
Publisher
Elsevier Science
Year
1986
Tongue
English
Weight
470 KB
Volume
137
Category
Article
ISSN
0006-291X

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## Abstract ## Background Formation and repair of DNA single-strand breaks are important parameters in the assessment of DNA damage and repair occurring in live cells. The 'Fluorimetric Detection of Alkaline DNA Unwinding (FADU)' method [Birnboim HC, Jevcak JJ. Cancer Res (1981) 41:1889–1892] is a