Graphite oxide mediated oxidative aromatization of 1,4-dihydropyridines into pyridine derivatives
โ Scribed by Maryam Mirza-Aghayan; Rabah Boukherroub; Mohammad Nemati; Mahshid Rahimifard
- Book ID
- 113930689
- Publisher
- Elsevier Science
- Year
- 2012
- Tongue
- French
- Weight
- 299 KB
- Volume
- 53
- Category
- Article
- ISSN
- 0040-4039
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๐ SIMILAR VOLUMES
A general and practical route for the high yield oxidative conversion of readily accessible 1,4-dihydropyridines to the corresponding pyridines is described using a relatively benign oxidant, manganese triacetate.
Manganese Triacetate Mediated Oxidation of Hantzsch 1,4-Dihydropyridines to Pyridines. -Alkyl, aryl, styryl, and heterocyclic substituents at the 4-position are tolerated in the practical and general method presented (11 examples). Reactions in several other solvents are very slow. A mechanism is d
Hantzsch 1,4-dihydropyridines were converted to the corresponding pyridines efficiently by sodium chlorite under mild conditions in excellent yields.