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Although total synthesis reached extraordinary levels of sophistication in the last century, the development of practical and efficient synthetic methodologies is still in its infancy. Achieving chemical reactions that are highly selective, economical, safe, resource-and energy-efficient, and environmentally benign is a primary challenge to chemistry in this century. Realizing this goal will demand the highest level of scientific creativity, insight and understanding in a combined effort by academic, government and industrial chemists and engineers. Advanced Synthesis & Catalysis promotes that process by publishing high-impact research results reporting the development and application of efficient synthetic methodologies and strategies for organic targets that range from pharmaceuticals to organic materials. Homogeneous catalysis, biocatalysis, organocatalysis and heterogeneous catalysis directed towards organic synthesis are playing an ever increasing role in achieving synthetic efficiency. Asymmetric catalysis remains a topic of central importance. In addition, Advanced Synthesis & Catalysis includes other areas that are making a contribution to green synthesis, such as synthesis design, reaction techniques, flow chemistry and continuous processing, multiphase catalysis, green solvents, catalyst immobilization and recycling, separation science and process development. Practical processes involve development of effective integrated strategies, from an elegant synthetic route based on mechanistic and structural insights at the molecular level through to process optimization at larger scales. These endeavors often entail a multidisciplinary approach that spans the broad fields chemistry, biology, and engineering and involve contributions from academic, government, and industrial laboratories. The unique focus of Advanced Synthesis & Catalysis has rapidly made it a leading organic chemistry and catalysis journal. The goal of Advanced Synthesis & Catalysis is to help inspire a new era of chemical science, based on the efforts of synthetic chemists and on interdisciplinary collaboration, so that chemistry will make an even greater contribution to the quality of life than it does now.
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