Graphene on Au(111): A Highly Conductive Material with Excellent Adsorption Properties for High-Resolution Bio/Nanodetection and Identification

✍ Scribed by Bo Song; Di Li; Wenpeng Qi; Marcus Elstner; Chunhai Fan; Haiping Fang

• Book ID: 102809989
• Publisher: John Wiley and Sons
• Year: 2010
• Tongue: English
• Weight: 663 KB
• Volume: 11
• Category: Article
• ISSN: 1439-4235
• DOI: 10.1002/cphc.200900743

✦ Synopsis

Abstract

Based on numerical simulations and experimental studies, we show that a composite material which consists of a sheet of graphene on a Au(111) surface exhibits both an excellent conductivity and the ability to stably adsorb biomolecules. If we use this material as a substrate, the signal‐to‐noise ratios can be greatly enhanced. The key to this unique property is that graphene can stably adsorb carbon‐based rings, which are widely present in biomolecules, due to π‐stacking interactions while the substrate retains the excellent conductivity of gold. Remarkably, the signal‐to‐noise ratio is found to be so high that the signal is clearly distinguishable for different nucleobases when an ssDNA is placed on this graphene‐on‐Au(111) material. Our finding opens opportunities for a range of bio/nano‐applications including single‐DNA‐molecule‐based biodevices and biosensors, particularly, high‐accuracy sequencing of DNA strands with repeating segments.