✦ LIBER ✦
Granulomatous prostatitis: A spectrum including nonspecific, infectious, and spindle cell lesions
✍ Scribed by Michael W. Stanley; Charles A. Horwitz; William Sharer; Erol Uke; Keith Kaye; Linda Burton
- Book ID
- 102139307
- Publisher
- John Wiley and Sons
- Year
- 1991
- Tongue
- English
- Weight
- 477 KB
- Volume
- 7
- Category
- Article
- ISSN
- 8755-1039
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✦ Synopsis
Most granulomas of the prostate are nonspec@c; infectious, postoperative, and allergic lesions are much less common. Fine-needle aspiration findings in the typical case are distinctive and easily recognized. Several series have been reported, but few have included histologic follow-up. We describe three cases of granulomatom prostatitis (GP) which showed a spectrum offindings confirmed by histologic sections. In all cases, carcinoma was suspected clinically. Case 1 represents typical nonspeci5c GP with epithelioid and multinucleated histiocytes. In case 2, aggregates of epithelioid histiocytes alternated with areas of necrosis and neutrophils. Histologically, the granulomas showed purulent centers. Silver stains revealed budding yeast in smears and sections. Cultures of FNA material subsequently revealed Cryptococcus.
In case 3, the histiocytes were predominantly spindled and occurred singly and in groups. The diyerential diagnosis included reactive and neoplastic spindle cell lesions. Histologic sections showed GP with spindled histiocytes. Appreciation of the broad cytologic spectrum of GP will facilitate accurate cytologic diagnosis. Diagn Cytopathol 1991;7:508-512.