Drug-induced hypersensitivity syndrome (DIHS), characterized by serious adverse systemic reactions in addition to skin rash, has unknown pathogenesis. Its association with human herpesvirus (HHV), mainly HHV-6, has been reported recently. A 46-year-old Japanese man is described in whom a generalized
โฆ LIBER โฆ
Granulomatous interstitial nephritis associated with atypical drug-induced hypersensitivity syndrome induced by carbamazepine
โ Scribed by Eriko Eguchi; Keiji Shimazu; Kensuke Nishiguchi; Soushi Yorifuji; Atsuo Tanaka; Takashi Kuwahara
- Publisher
- Springer
- Year
- 2011
- Tongue
- English
- Weight
- 377 KB
- Volume
- 16
- Category
- Article
- ISSN
- 1342-1751
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Hypersensitivity syndrome (HSS) usually refers to severe drug eruption associated with systemic symptoms and eosinophilia. Interleukin (IL)-5 regulates eosinophil counts with the help of IL-3 and granulocyte-macrophage colony-stimulating factor (GM-CSF). Blood IL-5 levels have been reported to be in