๐”– Bobbio Scriptorium
โœฆ   LIBER   โœฆ

Granulocyte-macrophage-colony stimulating factor in metastatic renal cell carcinoma : A phase II trial

โœ Scribed by Brian I. Rini; Walter M. Stadler; Ricardo T. Spielberger; Mark J. Ratain; Nicholas J. Vogelzang

Publisher
John Wiley and Sons
Year
1998
Tongue
English
Weight
87 KB
Volume
82
Category
Article
ISSN
0008-543X

No coin nor oath required. For personal study only.

โœฆ Synopsis

BACKGROUND.

Due to lack of success with standard chemotherapy and only modest

๐Ÿ“œ SIMILAR VOLUMES

Phase II trial of subcutaneously adminis
Phase II trial of subcutaneously administered granulocyte-macrophage colony-stimulating factor in patients with metastatic renal cell carcinoma
โœ Edward Wos; Thomas Olencki; Laurie Tuason; G. Thomas Budd; David Peereboom; Kate ๐Ÿ“‚ Article ๐Ÿ“… 1996 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 465 KB ๐Ÿ‘ 2 views

## BACKGROUND. Granulocyte-macrophage colony-stimulating factor (GM-CSF) is a cytokine that is involved in the differentiation and proliferation of various hematopoietic precursors. It also has been reported to enhance the antitumor activity of various mature effector cells. Previous reports have

Granulocyte-macrophageโ€“colony stimulatin
Granulocyte-macrophageโ€“colony stimulating factor in combination immunotherapy for patients with metastatic renal cell carcinoma : Results of two Phase II clinical trials
โœ Christopher W. Ryan; Nicholas J. Vogelzang; Mary C. Dumas; Timothy Kuzel; Walter ๐Ÿ“‚ Article ๐Ÿ“… 2000 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 94 KB ๐Ÿ‘ 2 views

The aim of this study was to determine the response rates and toxicity of two regimens containing granulocyte-macrophage-colony stimulating factor (GM-CSF) in combination with interleukin-2 (IL-2) in the treatment of patients with metastatic renal cell carcinoma. ## METHODS. Therapy given in the f

Granulocyte-macrophage-colony stimulatin
Granulocyte-macrophage-colony stimulating factor stimulates tumor invasiveness in squamous cell lung carcinoma
โœ Nobuko Tsuruta; Jun Yatsunami; Koichi Takayama; Youichi Nakanishi; Yukito Ichino ๐Ÿ“‚ Article ๐Ÿ“… 1998 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 300 KB ๐Ÿ‘ 1 views

## BACKGROUND. Bronchial epithelial cells produce a significant amount of granulocyte-macrophage-colony stimulating factor (GM-CSF), which is believed to mediate both the host defense and inflammation. Recently, GM-CSF has been demonstrated to be produced by several tumor cells and also to be asso

A Phase Ib/II trial of granulocyte-macro
A Phase Ib/II trial of granulocyte-macrophageโˆ’colony stimulating factor and interleukin-2 for renal cell carcinoma patients with pulmonary metastases : A case of fatal central nervous system thrombosis
โœ Kirsten M. Hotton; Masoud Khorsand; Jacquelyn A. Hank; Mark Albertini; Kyung Man ๐Ÿ“‚ Article ๐Ÿ“… 2000 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 187 KB ๐Ÿ‘ 1 views

## BACKGROUND. Interleukin-2 (IL-2) and granulocyte-macrophageฯชcolony stimulating factor (GM-CSF) are cytokines with nonoverlapping pleiotropic effects. In a prior Phase Ib study, this combination of agents exhibited antitumor effects in the lungs of four of eight patients with renal cell carcinoma