Granulocyte Colony-stimulating Factor-dependent Growth of an Acute Myeloblastic Leukemia Cell Line
โ Scribed by Nara, Nobuo ;Suzuki, Toshiya ;Nagata, Kaoru ;Tohda, Shuji ;Yamashita, Yoko ;Nakamura, Yuichi ;Imai, Yasufumi ;Morio, Tomohiro ;Minamihisamatsu, Masako
- Book ID
- 108579103
- Publisher
- Wiley (Blackwell Publishing)
- Year
- 1990
- Tongue
- English
- Weight
- 698 KB
- Volume
- 81
- Category
- Article
- ISSN
- 0910-5050
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The growth of the human leukemia cell line AML-193 in a serum-free medium is strictly dependent o n the presence of the cytokine granulocyte-macrophage COIL ony-stimulating factor (GM-CSF), which is one of the major regulators of the myelomonocytic lineage. At present, little is known about the mech
The use of granulocyte colony-stimulating factor (G-CSF) after chemotherapy for acute myeloblastic leukemia (AML) has been reported. However, there is a drawback in that G-CSF may stimulate the proliferation of AML progenitors. To determine the parameter(s) indicative of responsiveness of AML blasts