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Granular-cell tumor of trachea masquerading as hurthle-cell neoplasm on fine-needle aspirate: A case report

✍ Scribed by Esperanza B. Kintanar; Thomas J. Giordano; Norman W. Thompson; Claire W. Michael

Publisher: John Wiley and Sons
Year: 2000
Tongue: English
Weight: 189 KB
Volume: 22
Category: Article
ISSN: 8755-1039
DOI: 10.1002/(sici)1097-0339(200006)22:6<379::aid-dc10>3.0.co;2-3

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✦ Synopsis

We report on a case of extraluminal tracheal granular-cell tumor which was interpreted as a Hurthle-cell neoplasm of the thyroid on fine-needle aspirate. Review of the literature reveals only one other such case. The patient was a 35-yr-old female who presented with an enlarged thyroid. Aspiration cytology revealed a syncytium of cells with abundant granular cytoplasm interpreted as a thyroid follicular neoplasm with Hurthle-cell change. However, histology of the resection specimen with immunohistochemistry confirmed it as a granular-cell tumor. The cytologic differential diagnosis of neoplasms with oncocytoid cytoplasm in and around the thyroid should include granular-cell tumor of the trachea.

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