Gramicidin and Related Ion channel-Forming Peptides
β Scribed by J. Lundbaek
- Publisher
- Elsevier Science
- Year
- 2000
- Tongue
- English
- Weight
- 35 KB
- Volume
- 24
- Category
- Article
- ISSN
- 1065-6995
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
This review compares and contrasts the structures of several different types of ion channels with known three-dimensional structures, including gramicidin and the family of peptaibol channels, as well as the Streptomyces lividans potassium channel, to reveal common features in their structures that
## Abstract Zervamicin IIB (ZER) is a 16βmer peptaibol that produces voltageβdependent conductances in artificial membranes, a property considered responsible for its antimicrobial activity to mainly __Gram__βpositive microorganisms. In addition, ZER appears to inhibit the locomotor activity of the
To create ion channel function by synthetic peptides is a challenge in the de novo design of artificial membrane proteins. Amphiphilic a-helical motifs of Γ 20 amino acid residues to span lipid bilayers are most often used for the creation of peptide ion channels. Template molecules to tether helica