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Graft-versus-host reaction after blood transfusion in a patient with cellular immunodeficiency: The role of histocompatibility testing

✍ Scribed by D. Niethammer; S. F. Goldmann; H. -D. Flad; W. Meigel; U. Töllner; F. Pohlandt; B. Heymer; E. Kleihauer

Publisher: Springer
Year: 1979
Tongue: English
Weight: 706 KB
Volume: 132
Category: Article
ISSN: 0340-6997
DOI: 10.1007/bf00443203

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✦ Synopsis

A patient with an inborn cellular immunodeficiency syndrome developed a graft-versus-host reaction after a transfusion with packed red cells. This diagnosis was confirmed by skin biopsy and finally proved by tissue typing.

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A case of transfusion-induced graft-versus-host disease (GVHD) occurring in a 31-year-old female with Hodgkin's disease in complete remission is reported. Clinical features are similar to 19 other reported cases of transfusion-induced GVHD associated with malignant lymphoma. The lack of relationship