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Graft-versus-host disease-related polymyositis

✍ Scribed by Helene Maillard-Lefebvre; Sandrine Morell-Dubois; Marc Lambert; Hilaire Charlanne; David Launay; Eric Hachulla; Ibrahim Yakoub-Agha; Pierre-Yves Hatron


Publisher
Springer
Year
2010
Tongue
English
Weight
74 KB
Volume
29
Category
Article
ISSN
0770-3198

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Graft-versus-host disease (GVHD) has been the primary limitation to the wider application of allogeneic bone marrow transplantation (BMT). The pathophysiology of acute GVHD is complex and can be conceptualized to be a three-step process based on murine studies. In step 1, the conditioning regimen le