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Gradients of monoamine metabolites and cortisol in cerebrospinal fluid of psychiatric patients and healthy controls

✍ Scribed by Leif Bertilsson; Marie Åsberg; Olle Lantto; Gian-Paolo Scalia-Tomba; Lil Träskman-Bendz; Gunnel Tybring

Book ID
119094301
Publisher
Elsevier Science
Year
1982
Tongue
English
Weight
489 KB
Volume
6
Category
Article
ISSN
0165-1781

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Cerebrospinal fluid cyclic AMP and acid
Cerebrospinal fluid cyclic AMP and acid monoamine metabolites following probenecid: Studies in psychiatric patients
✍ Malcolm B. Bowers; Robert E. Study 📂 Article 📅 1979 🏛 Springer 🌐 English ⚖ 536 KB

At probenecid levels greater than 10 ~tg/ml, CSF cAMP was independent of CSF probenecid concentration. At these levels of probenecid, cAMP transport out of CSF is probably maximally blocked and cAMP levels reflect cAMP release into CSF. CSF cAMP was significantly higher in RDC-diagnosed schizophreni