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Gradient Distribution of LFA-1 cluster Size in the Immunological Synapse

✍ Scribed by Lin, Wan-Chen; Hartman, Niña C.; Groves, Jay T.

Book ID
122171936
Publisher
Biophysical Society
Year
2011
Tongue
English
Weight
33 KB
Volume
100
Category
Article
ISSN
0006-3495

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## Abstract Formation of immune synapses (IS) between T cells and APC requires multiple rearrangements in the actin cytoskeleton and selective receptor accumulation in supramolecular activation clusters (SMAC). The inner cluster (central SMAC) contains the TCR/CD3 complex. The outer cluster (periph