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Graded and binary responses in stochastic gene expression

✍ Scribed by Karmakar, Rajesh; Bose, Indrani


Book ID
118051826
Publisher
Institute of Physics
Year
2004
Tongue
English
Weight
269 KB
Volume
1
Category
Article
ISSN
1478-3967

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Inducible genes are expressed in the presence of an external stimulus. Individual cells may exhibit either a binary or graded response to such signals. It has been hypothesized that the chemical kinetics of transcription factor/DNA interactions can account for both these scenarios (EMBO J. 9(9) (199