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Grade of chemotherapy-induced necrosis as a predictor of local and systemic control in 881 patients with non-metastatic osteosarcoma of the extremities treated with neoadjuvant chemotherapy in a single institution

✍ Scribed by Gaetano Bacci; Mario Mercuri; Alessandra Longhi; Stefano Ferrari; Franco Bertoni; Michela Versari; Piero Picci


Book ID
116428572
Publisher
Elsevier Science
Year
2005
Tongue
English
Weight
111 KB
Volume
41
Category
Article
ISSN
0959-8049

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The feasibility of neoadjuvant high-dose
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## Abstract ## BACKGROUND The primary and secondary objectives of the current study were to improve the β‰₯ 90% tumor necrosis rate and assess the toxicity profile of the neoadjuvant high‐dose chemotherapy (HDC) regimen, respectively. ## METHODS Twenty‐two patients with AJCC Stage IIB high‐grade o