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GPX Pro198Leu and OGG1 Ser326Cys polymorphisms and risk of development of colorectal adenomas and colorectal cancer

✍ Scribed by Rikke Hansen; Mona Sæbø; Camilla Furu Skjelbred; Bjørn Andersen Nexø; Per Christian Hagen; Günther Bock; Inger Marie Bowitz Lothe; Egil Johnson; Steinar Aase; Inger-Lise Hansteen; Ulla Vogel; Elin H. Kure

Book ID
116333763
Publisher
Elsevier Science
Year
2005
Tongue
English
Weight
111 KB
Volume
229
Category
Article
ISSN
0304-3835

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✍ Anita Koushik; Gregory J. Tranah; Jing Ma; Meir J. Stampfer; Howard D. Sesso; Ch 📂 Article 📅 2006 🏛 John Wiley and Sons 🌐 French ⚖ 98 KB

## Abstract A single nucleotide polymorphism (SNP) at codon 72 of the __p53__ gene (Arg72Pro) alters the p53 protein structure and affects its activity. We investigated this SNP in relation to colorectal adenoma and cancer among men and women from case–control studies nested within the Nurses' Heal