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GPR30 and estrogen receptor expression: new insights into hormone dependence of inflammatory breast cancer

✍ Scribed by Hugo Arias-Pulido; Melanie Royce; Yun Gong; Nancy Joste; Lesley Lomo; Sang-Joon Lee; Nabila Chaher; Claire Verschraegen; Juanita Lara; Eric R. Prossnitz; Massimo Cristofanilli

Publisher: Springer US
Year: 2009
Tongue: English
Weight: 357 KB
Volume: 123
Category: Article
ISSN: 0167-6806
DOI: 10.1007/s10549-009-0631-7

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## Abstract Expression of an estrogen receptor α (ER) transgene in hormone independent breast cancer and normal breast epithelial cells arrests cell cycling when estradiol is added. Although endogenously expressed ER does not typically affect estradiol‐induced cell cycling of hormone dependent brea