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GPCR signaling induces activity-dependent gene expression through activation of NMDA receptor

✍ Scribed by Minami Inoue; Mamoru Fukuchi; Yuki Kuwana; Ichiro Takasaki; Akiko Tabuchi; Masaaki Tsuda

Book ID
116778868
Publisher
Elsevier Science
Year
2011
Tongue
English
Weight
127 KB
Volume
71
Category
Article
ISSN
0168-0102

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## Abstract Chemical transmitters released from astrocytes, termed gliotransmitters, modulate synaptic transmission and neuronal function. Using astrocyte‐specific inducible transgenic mice (dnSNARE mice), we have demonstrated that inhibiting gliotransmission leads to reduced activation of adenosin