𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Goodpasture's syndrome in childhood: Treatment with plasmapheresis and immunosuppression

✍ Scribed by Leo J. McCarthy; Jenny Cotton; Constance Danielson; Vicki Graves; Jerry Bergstein


Publisher
John Wiley and Sons
Year
1994
Tongue
English
Weight
465 KB
Volume
9
Category
Article
ISSN
0733-2459

No coin nor oath required. For personal study only.

✦ Synopsis


Abstract

Goodpasture's syndrome rarely affects children. Therefore, we present our experience in a young boy whose pulmonary hemorrhage was dramatically resolved by three plasma exchanges. We believe the hemorrhage was caused primarily by acute capillaritis. He received cytoxan and steroids and a series of plasma exchanges which removed/suppressed his anti‐glomerular basement membrane (anti‐GBM) antibody production. However, after a year, his renal function did not return, and he required renal transplantation and continues to do well.


📜 SIMILAR VOLUMES


Remission of hyper-lgE syndrome treated
✍ Peter C. Dau 📂 Article 📅 1988 🏛 John Wiley and Sons 🌐 English ⚖ 969 KB

A patient with a hyper-IgE syndrome was treated with 60 plasmaphereses over a period of 2 years in conjunction with cytotoxic immunosuppressive drug therapy. During this time her severe dermatitis of 8 years' duration became almost completely inactive, and her circulating IgE level was reduced by 73

Manual plasmapheresis in the treatment o
✍ Nandrani S. De Zoysa; K. K. D. G. Jayaweera; Thiru Vaithianathan 📂 Article 📅 1994 🏛 John Wiley and Sons 🌐 English ⚖ 376 KB 👁 1 views

## Abstract We report on 41 patients with Guillain‐Barré Syndrome (GBS) with disability grade 4 and 5 who were treated with manual plasma exchange (PE). Approximately 20‐40 ml/kg body weight of plasma was removed with each manual PE; 63% of patients needed one PE, 24% needed two, 10% needed three,

Experience of double filtration plasmaph
✍ Wei-Hung Chen; Jiann-Horng Yeh; Hou-Chang Chiu 📂 Article 📅 1999 🏛 John Wiley and Sons 🌐 English ⚖ 26 KB 👁 1 views

Therapeutic plasma exchange (TPE) is a standard treatment in Guillain-Barre ´syndrome. TPE may require exogenous fluid for replacement of plasma and, depending on the equipment used, varying extracorporeal volumes. Potential adverse effects include allergic reaction, infection, and hypotension. From