Goodpasture syndrome during the course of a Schönlein-Henoch purpura

✍ Scribed by Luis Carreras; Rafael Poveda; Jordi Bas; Mariona Mestre; Inés Rama; Marta Carrera

• Book ID: 114463632
• Publisher: Elsevier Science
• Year: 2002
• Tongue: English
• Weight: 97 KB
• Volume: 39
• Category: Article
• ISSN: 0272-6386
• DOI: 10.1053/ajkd.2002.32799

✦ Synopsis

Two months after surgical resection of a bronchogenic carcinoma, a 69-year-old patient presented with Scho ¨nlein-Henoch purpura with kidney involvement followed by pulmonary hemorrhage. The presence of an IgA linear pattern on the kidney biopsy specimen and circulating anti-glomerular basement membrane (GBM) IgA antibodies led to the diagnosis of Goodpasture syndrome, which implies the possibility that the well-known pulmonary involvement during the course of Scho ¨nlein-Henoch purpura could be caused by Goodpasture syndrome in certain cases. In cases of glomerulonephropathy with lung involvement, clinicians should not limit their investigations to anti-GBM IgG.