𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Good cell, bad cell: Flow cytometry reveals T-cell subsets important in HIV disease

✍ Scribed by Pratip K. Chattopadhyay; Mario Roederer

Book ID
102137382
Publisher
John Wiley and Sons
Year
2010
Tongue
English
Weight
149 KB
Volume
77A
Category
Article
ISSN
0196-4763

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✦ Synopsis

Abstract

Flow cytometry is a key technology in the study of HIV disease. In this article, we review various cellular markers that can be measured in the setting of pathogenesis or vaccination studies, including markers of activation, differentiation, senescence, immune suppression, and function. In addition, we discuss important considerations for making these measurements. Finally, we examine how flow cytometry studies have taught researchers about the disease process, and the potential for flow cytometry technology to guide treatment decisions and evaluate vaccine candidates in the future. Published 2010 Wiley‐Liss, Inc.

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