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Gonadoblastoma and Y-chromosome fluorescence

✍ Scribed by T. Lukusa; J. P. Fryns; H. van den Berghe

Book ID
115089502
Publisher
John Wiley and Sons
Year
2008
Tongue
English
Weight
363 KB
Volume
29
Category
Article
ISSN
0009-9163

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Gonadoblastoma is a rare tumor arising in the streak gonads of about 30% of 46,XY sex-reversed females. Because gonadoblastoma develops only in patiems who have Y-chromosome material and dysgenetic gonads, it has been hypothesized that positive expression of a gene (or genes) on the Y chromosome (GB