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Gonadal dysfunction due to cis-platinum

โœ Scribed by Wallace, W. H. B. ;Shalet, S. M. ;Crowne, E. C. ;Morris-Jones, P. H. ;Gattamaneni, H. R. ;Price, D. A.


Publisher
John Wiley and Sons
Year
2006
Tongue
English
Weight
492 KB
Volume
17
Category
Article
ISSN
0098-1532

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We describe a case of XY sex reversal, gonadal dysgenesis, and gonadoblastoma in a patient with a deletion of 9p24 due to a familial translocation. The rearranged chromosome 9 was inherited from the father; the patient's karyotype was 46,XY,der(9)t(8;9) (p21;p24)pat. A review shows that 6 additional