✦ LIBER ✦
Gold-Catalysed Oxyarylation of Styrenes and Mono- and gem-Disubstituted Olefins Facilitated by an Iodine(III) Oxidant
✍ Scribed by Liam T. Ball; Prof. Dr. Guy C. Lloyd-Jones; Dr. Christopher A. Russell
- Publisher
- John Wiley and Sons
- Year
- 2012
- Tongue
- English
- Weight
- 300 KB
- Volume
- 18
- Category
- Article
- ISSN
- 0947-6539
No coin nor oath required. For personal study only.
✦ Synopsis
Abstract
1‐Hydroxy‐1,2‐benziodoxol‐3(1__H__)‐one (IBA) is an efficient terminal oxidant for gold‐catalysed, three‐component oxyarylation reactions. The use of this iodine(III) reagent expands the scope of oxyarylation to include styrenes and gem‐disubstituted olefins, substrates that are incompatible with the previously reported Selectfluor‐based methodology. Diverse arylsilane coupling partners can be employed, and in benzotrifluoride, homocoupling is substantially reduced. In addition, the IBA‐derived co‐products can be recovered and recycled.