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Gnotobiotic Toll-Like Receptor 5 Deficient Mice Lack Spontaneous Colitis and Metabolic Syndrome

✍ Scribed by Vijay-Kumar, Matam ;Aitken, Jesse D. ;Su, Yueju ;Srinivasan, Gayathri ;Carvalho, Frederic A. ;Gewirtz, Andrew T.

Book ID: 122332673
Publisher: Elsevier Science
Year: 2011
Tongue: English
Weight: 44 KB
Volume: 140
Category: Article
ISSN: 0016-5085
DOI: 10.1016/S0016-5085(11)61314-0

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## Background: Toll-like receptor 5 (tlr5) is implicated in the innate and adaptive immune responses that are associated with inflammatory bowel disease (ibd). in humans tlr5 is expressed on cd4(+) t cells and costimulation with flagellin potentiates effector and regulatory t cell responses. the ai