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Gnidilatimonoein triggers cell cycle arrest and apoptosis in chronic myelogenous leukemia cells

✍ Scribed by Nouri Kazem; Yazdanparast Razieh

Book ID: 118431221
Publisher: Elsevier Science
Year: 2011
Tongue: English
Weight: 52 KB
Volume: 44
Category: Article
ISSN: 0009-9120
DOI: 10.1016/j.clinbiochem.2011.08.517

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## Abstract Mycophenolic acid (MPA) specifically inhibits inosine‐5′‐monophosphate dehydrogenase, the first committed step toward GMP biosynthesis. In its morpholinoethyl ester pro‐drug form it is one of the most promising immunosuppressive drugs recently developed. The aim of the present study was