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GMP-140, a receptor that mediates interactions of leukocytes with activated platelets and endothelium

โœ Scribed by Rodger P. McEver


Book ID
113409329
Publisher
Elsevier Science
Year
1991
Tongue
English
Weight
795 KB
Volume
1
Category
Article
ISSN
1050-1738

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GMP-140: A receptor for neutrophils and
โœ Dr. Rodger P. McEver ๐Ÿ“‚ Article ๐Ÿ“… 1991 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 743 KB

GMP-140 is a membrane glycoprotein located in secretory granules of platelets and endothelium. When these cells are activated by agonists such as thrombin, GMP-140 is rapidly translocated to the plasma membrane. GMP-140, along with ELAM-1 and the peripheral lymph node homing receptor, defines the se